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Systematic review of interventions for pre-frail and frail older adults: Evidence from clinical trials on frailty levels - PubMed

3 hours ago
  • #frailty interventions
  • #systematic review
  • #older adults
  • Pre-frailty and frailty affect 54.1% and 26.3% of older adults, leading to adverse outcomes.
  • Physical exercise interventions made up 42.5% of studies, with multicomponent programs at 27.5%.
  • Improvements in frailty levels were reported in 32.5% of studies, with gains in quality of life (+15.2%), gait speed (+0.22 m/s), and muscle strength (+18.7%).
  • Pre-frail individuals showed the greatest responsiveness to interventions due to their remaining adaptability.
  • Multifaceted interventions were effective, emphasizing standardized frailty assessment criteria and physical activity as key.
  • Integrated interventions significantly enhance health, highlighting the need for early, tailored, multidisciplinary strategies.