Mitochondrial dynamics in neurodevelopment and neurodevelopmental disorders - PubMed
12 hours ago
- #neurodevelopment
- #NDDs
- #mitochondria
- Mitochondrial deficits are observed in neurodevelopmental disorders (NDDs) like autism spectrum disorder (ASD).
- The role of mitochondrial dynamics (fusion, fission, transport) in brain development and NDDs is not fully understood.
- Most studies focus on metabolic consequences of mitochondrial dysfunction rather than dynamics.
- Recent advances highlight mechanisms regulating mitochondrial dynamics during neurodevelopment.
- Genetic and epigenetic alterations affecting mitochondrial dynamics may contribute to NDDs.
- Mitochondrial dynamics could be a potential therapeutic target for NDDs.