A bibliometric analysis of alpha-synuclein in Parkinson's disease from 2015 to 2024 - PubMed
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- #alpha-synuclein
- #Parkinson's disease
- #bibliometric analysis
- Bibliometric analysis of alpha-synuclein in Parkinson's disease from 2015 to 2024.
- 10,390 publications analyzed with steady annual growth (R2 = 0.8741).
- Top contributing countries: United States, China, and Germany.
- Leading institutions include University of Cambridge and University of Pennsylvania.
- Core journals: Movement Disorders and International Journal of Molecular Sciences.
- Research hotspots: neurodegeneration, aggregation, oxidative stress, Lewy bodies, and diagnostic technologies like RT-QuIC.
- Important trends: immune mechanisms, exosome-mediated propagation, gut-brain axis involvement, and cross-disease mechanisms.
- Future research should focus on mechanistic studies, biomarker validation, and targeted therapies for personalized medicine.