TREM2 in neurodegeneration and diseases - PubMed
5 days ago
- #TREM2
- #Neurodegeneration
- #Microglia
- TREM2 is a cell surface receptor mainly found on microglia in the CNS.
- TREM2 signaling regulates neuroinflammation and neurodegeneration, especially in Alzheimer's and Parkinson's diseases.
- The review focuses on TREM2's role in AD and PD, discussing recent preclinical studies.
- The aim is to enhance understanding of microglial function in AD and PD pathology.
- The review hopes to inspire new therapeutic interventions for neurodegenerative diseases.