A Randomized Trial of Targeted Hyponatremia Correction in Hospitalized Patients - PubMed
6 hours ago
- #randomized-trial
- #hospitalized-patients
- #hyponatremia
- A randomized trial evaluated targeted hyponatremia correction versus routine care in hospitalized patients.
- The study involved 2173 patients across nine European centers with plasma sodium levels below 130 mmol/l.
- The intervention group showed a higher correction rate to normal sodium levels (60.4%) compared to the control group (46.2%).
- No significant difference was found in the primary outcome of 30-day mortality or rehospitalization between groups.
- Overcorrection occurred slightly more in the intervention group (2.3%) than in the control group (1.4%), with no cases of osmotic demyelination syndrome.