Genomic and population analyses reveal asymmetric subgenome evolution and local adaptation in the polyploid Lycopus lucidus - PubMed
4 hours ago
- #subgenome asymmetry
- #polyploid evolution
- #local adaptation
- Recent whole-genome triplication occurred in Lycopus lucidus, with three subgenomes (A, B, C) showing asymmetric evolution in transposable elements, gene retention, and evolutionary rates.
- Subgenome B is stabilized under purifying selection, while subgenomes A and C have dynamic reorganization with accelerated gene turnover and asymmetric selection pressures.
- Population analysis identifies four genetic lineages linked to geography, with a demographic bottleneck during late Holocene cooling.
- 93.8% of genes under selection between lineages originate from subgenome C, highlighting its role as a reservoir for adaptive variation.
- Genotype-environment associations reveal 9,496 adaptive SNPs enriched in stress response, secondary metabolism, and wax biosynthesis, primarily driven by precipitation for local adaptation.