Regulating the crosstalk between Bifidobacterium and the brain: a potential therapeutic strategy for Alzheimer's disease - PubMed
2 days ago
- #Alzheimer's disease
- #Bifidobacterium
- #gut-microbe-brain axis
- Alzheimer's disease (AD) is a common dementia in the elderly, characterized by cognitive impairment and memory loss.
- Pathological features of AD include amyloid-β (Aβ) deposition and tau phosphorylation.
- The gut microbiome, particularly Bifidobacterium, is altered in AD patients, suggesting a potential link to disease pathogenesis.
- Bifidobacterium plays a key role in maintaining gut flora balance and may influence AD via the gut-microbe-brain axis.
- Current research on Bifidobacterium's mechanisms in alleviating AD is limited, highlighting the need for further investigation.
- This review explores Bifidobacterial changes in AD and their potential as a therapeutic strategy.