Mitochondria-Targeted Biophysical Priming of Autologous Biologics for Skin Regeneration and Wound Repair - PubMed
6 hours ago
- #biophysical priming
- #mitochondria
- #skin regeneration
- Mitochondria-centered mechanisms drive skin aging, photoaging, and chronic wounds through oxidative stress and impaired bioenergetics.
- Autologous biologics like platelet-rich plasma (PRP) and mesenchymal stromal cells (MSCs) are used for skin rejuvenation and wound repair, with effects mediated by mitochondrial mechanisms.
- Biophysical modalities such as photobiomodulation (PBM) and low-intensity pulsed ultrasound (LIPUS) can modulate mitochondrial function in skin cells.
- The review introduces the concept of mitochondria-targeted biophysical priming of autologous biologics for dermatological applications.
- Key regulatory considerations for clinical translation are discussed.