5x-Multiplier Versus 3-Tier Model: A Pragmatic Randomized Clinical Trial for Discharge Opioid Prescriptions After Intra-Abdominal Cancer Surgery - PubMed
5 hours ago
- #Clinical Trial
- #Cancer Surgery
- #Opioid Prescribing
- This study compared two discharge opioid prescribing models for patients undergoing intra-abdominal cancer surgery.
- Patients were randomized to either a 5x-multiplier algorithm (last 24-hour OME multiplied by 5) or a capped 3-tier model (5/15/30 pills based on OME).
- The 5x-multiplier group received significantly fewer discharge opioids (median 25 mg OME) compared to the 3-tier group (75 mg OME), with 44% discharged opioid-free.
- There was no significant difference in 14-day post-discharge opioid consumption, refill rates, patient satisfaction, or symptom inventory scores between the two models.
- The 5x-multiplier model resulted in fewer prescribed opioids while maintaining similar patient outcomes and satisfaction.