Hepatitis B Surface Antigen Loss and Improved Clinical Outcomes in US Individuals With Chronic Hepatitis B Virus Infection - PubMed
a day ago
- #hepatitis B
- #clinical outcomes
- #HBsAg loss
- HBsAg loss in chronic HBV patients is linked to significantly reduced risks of hepatocellular carcinoma (89% lower) and all-cause mortality (62% lower).
- The study, using US electronic health records, included 15,760 chronic HBV patients, with 4.2% experiencing HBsAg loss over the study period.
- HBsAg loss also showed reduced, though not statistically significant, risks for compensated cirrhosis and decompensated liver disease.
- The research highlights HBsAg loss as a proxy for functional cure, supporting improved clinical outcomes in a diverse US population.