Pharmacokinetics, Bioequivalence, and Safety Evaluation of Two Voriconazole Tablets in Healthy Chinese Volunteers - PubMed
5 hours ago
- #Bioequivalence
- #Voriconazole
- #Pharmacokinetics
- The study assessed the pharmacokinetics, bioequivalence, and safety of two oral voriconazole tablets in healthy Chinese volunteers under fasting conditions.
- A single 200 mg dose of generic (test) or branded (reference) voriconazole was given in a crossover trial, with 68 participants included in the final analysis.
- Geometric mean ratios for Cmax, AUC0-t, and AUC0-inf were 1.03, 0.98, and 0.97, respectively, meeting bioequivalence criteria, and both formulations were well-tolerated.