Migraine impairs the auditory protective mechanism: a potential biomarker - PubMed
5 hours ago
- #Migraine
- #Auditory Pathways
- #Biomarker
- Migraine patients show dysfunction in auditory efferent pathways, specifically in the medial olivocochlear reflex (MOCR) and middle ear muscle reflex (MEMR).
- Elevated contralateral acoustic reflex thresholds (ARTs) at 500 Hz and 1000 Hz indicate MEMR impairment in migraine groups.
- Reduced distortion-product otoacoustic emissions (DPOAE) suppression reflects MOCR dysfunction in migraine patients.
- Auditory efferent disruption is intrinsic to migraine pathophysiology and independent of tinnitus comorbidity.
- Contralateral ART may serve as an objective biomarker for migraine-related auditory pathway involvement.