Joint associations of anthropometric indices and C-reactive protein-triglyceride-glucose index with incident hypertension: a stratified analysis by blood pressure level from the CHARLS, 2011-2020 - Pu
6 hours ago
- #metabolic markers
- #hypertension
- #longitudinal study
- Study examines joint associations of anthropometric indices and C-reactive protein-triglyceride-glucose index (CTI) with incident hypertension.
- Data from CHARLS (2011-2020) involving 4,735 participants (median age 56, 46.04% male) with 1,852 developing hypertension over 9 years.
- Higher levels of both anthropometric indices and CTI linked to the highest hypertension risk (HR=1.51 in total population).
- Combination of BRI and CTI showed best predictive performance (AUC=0.747) and improved risk discrimination.
- CTI mediated the association between anthropometric indices and hypertension, suggesting pathways involving insulin resistance and inflammation.
- Findings applicable across different baseline blood pressure levels, emphasizing the importance of integrated metabolic and obesity markers.