The MEK1/2-IRF4 axis fosters T follicular helper cell differentiationand antitumor humoral immune response - PubMed
5 hours ago
- #Antitumor immunity
- #MEK1/2-IRF4 axis
- #T follicular helper cells
- The MEK1/2-IRF4 axis promotes T follicular helper (Tfh) cell differentiation and antitumor humoral immune response.
- Animal experiments were approved by the Institutional Animal Care and Ethics Committee of Huazhong University of Science and Technology (Approval #4835).
- The study highlights the role of Tfh cells in antitumor immunity and immunotherapy.
- Key references include studies on Tfh cell biology, autoimmunity, and their roles in allergic diseases and cancer.