Cardiac Screening for Conditions Associated With Sudden Cardiac Death: Yield, Interventions, and SCA/SCD Incidence in 104,369 Young Individuals - PubMed
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- #cardiac screening
- #sudden cardiac death
- #preventive cardiology
- Cardiac screening in 104,369 young individuals (aged 14-35) identified conditions associated with sudden cardiac arrest/death (SCA/SCD) in 0.3% of cases.
- 41% of those diagnosed with SCA/SCD-related conditions received risk-modifying interventions, including 10 prophylactic implantable cardioverter defibrillators and 2 cardiac transplants.
- Over a 6-year follow-up, 0.08% of initially cleared individuals were later diagnosed with SCA/SCD-related conditions or experienced SCA/SCD events.
- The incidence of SCA/SCD was 5.6 per 100,000 person-years, with a median age of presentation at 23.8 years.
- ECG showed higher sensitivity (75.4%) than the questionnaire (32.5%) for detecting SCA/SCD-related conditions.
- Serial evaluations may help address age-related penetrance challenges in SCA/SCD prevention.