Mortality Predictions Including Pre-Admission Functional Status in ICU Patients With Delirium-A Substudy of the AID-ICU Trial - PubMed
5 hours ago
- #delirium
- #mortality-prediction
- #ICU
- Study aimed to develop clinical prediction models for 90-day and 1-year mortality in ICU patients with delirium, incorporating pre-admission functional status.
- 632 participants from the AID-ICU trial were included, with data on frailty, comorbidity, and functional status.
- Elastic net regression models showed fair discrimination (AUC ~0.74) and good calibration for both 90-day and 1-year mortality predictions.
- Key predictors included frailty, age, Simplified Mortality Score for ICU (SMS-ICU), advanced cancer, and surgical admission.
- Models may help identify high-risk patients for targeted clinical assessment and follow-up, though individual-level predictions should be cautious.
- Future studies needed to validate models in other ICU settings and assess clinical utility.