Persistent PI3K-AKT signaling fortifies cellular defense against oxidative stress and ferroptosis through augmented mitochondrial fitness - PubMed
6 hours ago
- #Ferroptosis
- #Oxidative stress
- #PI3K-AKT signaling
- Persistent PI3K-AKT signaling enhances cellular defense against oxidative stress and ferroptosis.
- The study highlights the role of augmented mitochondrial fitness in this protective mechanism.
- Key topics include Ferroptosis resistance, Mitochondrial fitness, Oncogenic pathways, Oxidative stress, and PI3K–AKT signaling.
- The authors declare no competing interests and all approved the final version for publication.
- References include studies on reactive oxygen species (ROS), redox regulation, and their roles in cancer and cellular responses.