Associations of DTI-ALPS index and choroid plexus volume with clinical severity across the Parkinson's disease spectrum - PubMed
5 hours ago
- #Parkinson's disease
- #neuroimaging
- #brain clearance
- Lower DTI-ALPS index correlates with increased motor severity in prodromal and PD patients.
- Lower DTI-ALPS index is associated with RBD, cognitive impairment, and depressive symptoms.
- NCPV shows positive associations with clinical severity and negatively correlates with the ALPS index.
- DTI-ALPS index declines with age, is lower in males, and decreases from controls to PD patients.
- MRI markers linked to brain clearance processes are associated with PD progression and staging.