Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications - PubMed
5 hours ago
- #disease-transmission
- #viromics
- #herbivores
- Study on domestic herbivore viruses in China reveals transmission dynamics and disease management implications.
- Pan-viromic profiling of 10,225 swabs and 4,304 serum samples from 5,710 individuals across five major herbivore-rearing provinces.
- Creation of the domestic herbivore viromic catalog of China (DhCN-Virome) with 1,085,360 viral metagenomes.
- Distinct viromic signatures observed across herbivore species and sample types.
- Viral communities follow a 'higher openness, greater stability' pattern, with confined animals more susceptible to external influences.
- Viral circulations occur within herbivore species and extensively between herbivores and other species, including humans and birds.
- Bacteriophages are the most abundant viral entities, with lytic replication strategies targeting pathogenic bacterial hosts.
- Findings highlight the need for unified disease management strategies and urgent epidemiological surveillance and vaccination programs.