Effects of Exercise and Intensive Vascular Risk Reduction on Cognitive Function in Older Adults: A Randomized Clinical Trial - PubMed
4 hours ago
- #exercise
- #cognitive function
- #vascular risk reduction
- The study investigated the effects of exercise and intensive vascular risk reduction (IRVR) on cognitive function in older adults.
- Participants were randomized into four groups: aerobic exercise, IRVR, IRVR + exercise, and usual care.
- Primary outcome was change in global cognitive function measured by the Preclinical Alzheimer Cognitive Composite (PACC) score over 24 months.
- No statistically significant differences in cognitive improvements were found between the intervention groups and usual care.
- Secondary outcomes, including the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) scores, also showed no significant differences.
- The study concluded that neither exercise, IRVR, nor their combination significantly improved cognitive function in older adults at risk for dementia.