Associations between respiratory diseases and lung cancer risk: a secondary analysis of the large-scale prospective UK biobank cohort - PubMed
6 hours ago
- #Acute Infections
- #Respiratory Diseases
- #Lung Cancer Risk
- Respiratory diseases are associated with increased lung cancer risk (HR 2.97).
- Acute respiratory infections show strong associations with lung cancer incidence, especially viral pneumonia (HR 9.86).
- Squamous cell carcinoma exhibits the highest risk elevation among subtypes (HR 3.65).
- Neutrophil counts partially mediate the associations (up to 8% mediated).
- Study uses UK Biobank cohort data with 2189 lung cancer cases over mean 10.44-year follow-up.