Antidepressants and bleeding risk: Expert consensus from the Association of Medicine and Psychiatry - PubMed
6 hours ago
- #antidepressants
- #bleeding-risk
- #clinical-guidelines
- Antidepressants, especially serotonin-reuptake inhibitors (SRIs), may increase bleeding risk, particularly in patients with other risk factors.
- A PubMed literature search (1992-2024) informed expert consensus recommendations from the Association of Medicine and Psychiatry.
- Consensus includes guidelines and a clinical decision algorithm for managing antidepressants in patients at risk for bleeding.
- The algorithm helps clinicians decide on initiating, discontinuing, or adjusting antidepressants while balancing risks and benefits.
- Additional studies are needed to refine clinical decision-making for patients with complex medical and psychiatric conditions.