Baicalin as a Multifunctional Regulator of Gut Health: Integrative Mechanisms Involving Inflammation, Barrier Integrity, and Gut-Organ Axis - PubMed
5 hours ago
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- #baicalin
- #gut health
- Baicalin (BAI) is a flavonoid from Scutellaria baicalensis that regulates gut health.
- BAI modulates inflammation by targeting NF-κB signaling and immune cell responses.
- It enhances gut barrier integrity by preserving tight junctions and mucus layers.
- BAI influences gut microbiota and microbial metabolites like short-chain fatty acids.
- Potential benefits extend to gut-organ axes, such as gut-liver and gut-metabolic interactions.
- Challenges include low oral bioavailability and the need for clinical validation.