Management of Postmenopausal Osteoporosis - PubMed
6 hours ago
- #fracture-prevention
- #osteoporosis
- #postmenopausal
- Postmenopausal women experience ongoing bone loss, increasing fracture risk.
- Lifestyle measures include balanced diet, physical activity, avoiding smoking, and moderating alcohol.
- Severe vitamin D deficiency accelerates bone loss and should be avoided.
- Falls prevention is crucial as falls cause most fractures.
- Pharmaceuticals for osteoporosis either inhibit bone resorption or stimulate bone formation.
- Bisphosphonates are widely used anti-resorptives, with zoledronate having long-lasting effects.
- Denosumab prevents fractures but has rapid offset after cessation.
- Anabolic agents like romosozumab show broad anti-fracture efficacy but are used short-term.
- Treatment sequences need more research for optimal fracture reduction.