Oligofructose alleviates hyperandrogenism in polycystic ovary syndrome through gut microbiota-derived bile acids - PubMed
6 hours ago
- #PCOS
- #bile acids
- #gut microbiota
- Oligofructose (OFS) improves reproductive and metabolic issues in a PCOS mouse model.
- Benefits of OFS depend on gut microbiota and bile acids, specifically hyodeoxycholic acid (HDCA).
- HDCA increases estradiol production and aromatase activity in ovarian cells via TGR5 signaling.