Nutraceuticals and the Microbiota-Gut-Brain Axis: A Pathway for Preventing Cognitive Decline - PubMed
5 hours ago
- #cognitive decline
- #nutraceuticals
- #gut-brain axis
- Cognitive impairment and neurodegenerative diseases like Alzheimer's are increasing due to aging populations.
- Current treatments focus on symptoms, not causes, prompting exploration of alternative strategies like nutraceuticals.
- Nutraceuticals (e.g., vitamins, omega-3s, polyphenols) show neuroprotective effects via antioxidant, anti-inflammatory, and mitochondrial support.
- The gut microbiota influences the bioavailability and effectiveness of nutraceuticals.
- Microbiome interventions (prebiotics, probiotics, fecal transplants) may help modulate neuroinflammation and cognitive function.
- Nutraceuticals and microbiome-targeted strategies offer low-risk options for preventing cognitive decline.
- Further large-scale studies are needed to confirm efficacy and personalize approaches based on microbiome profiles.