Association of leuko-glycemic index with mortality in critically ill stroke patients: analysis from the MIMIC-IV database and an institutional cohort - PubMed
5 hours ago
- #mortality
- #biomarker
- #stroke
- The leuko-glycemic index (LGI) combines white blood cell count and blood glucose to reflect systemic inflammation and stress hyperglycemia.
- The study evaluated LGI's association with mortality in critically ill stroke patients using the MIMIC-IV database and an institutional cohort.
- Patients in the highest LGI quartile had a threefold higher risk of 28-day mortality compared to the lowest quartile.
- LGI was also positively associated with 365-day mortality and in-hospital mortality in both cohorts.
- Spline analyses showed mortality risk increased steeply from low to moderate LGI levels and more gradually at higher levels.
- Subgroup analyses confirmed consistent positive associations across most clinical strata.
- LGI may serve as a simple biomarker for early risk stratification in critically ill stroke patients.