Metformin Use and Development of Esophageal Squamous Cell Carcinoma - PubMed
6 hours ago
- #Metformin
- #Esophageal Cancer
- #Preventive Medicine
- Metformin use is associated with a 36% lower odds of developing esophageal squamous cell carcinoma (ESCC).
- The study was a population-based case-control analysis across five Nordic countries (Denmark, Finland, Iceland, Norway, Sweden).
- Higher metformin dosage (>1278 defined daily dose in 5 years) showed even greater reduction in ESCC risk (OR, 0.52).
- Findings suggest metformin could be explored as a preventive measure or therapeutic option for ESCC in high-risk individuals.