Survival benefit of ⁶⁸Ga-FAPI PET/CT staging for prognostic assessment in gastric and colorectal cancer compared with CE-CT and ¹⁸F-FDG PET/CT: a single-center retrospective study - PubMed
5 hours ago
- #PET/CT imaging
- #cancer prognosis
- #survival analysis
- Study compares 68Ga-FAPI PET/CT with CE-CT and 18F-FDG PET/CT for staging in gastric and colorectal cancer, focusing on survival outcomes.
- 68Ga-FAPI PET/CT significantly improved median overall survival for both cancers compared to other imaging methods.
- 68Ga-FAPI PET/CT increased staging accuracy, altered staging in 41%-52% of patients, and reduced unnecessary surgeries by 42%-69%.
- Cox multivariate regression identified CE-CT and 18F-FDG PET/CT as prognostic risk factors relative to 68Ga-FAPI PET/CT.
- Improvements in survival are linked to better staging accuracy and more appropriate treatment decisions.