Resuscitation From Out-of-Hospital Cardiac Arrest When Is EtCO2 Reliably Associated With ROSC? - PubMed
a day ago
- #EtCO2
- #Resuscitation
- #OHCA
- End-tidal carbon dioxide (EtCO2) trajectories are linked to outcomes in out-of-hospital cardiac arrest (OHCA).
- Study aimed to determine minimum EtCO2 monitoring duration needed to distinguish return of spontaneous circulation (ROSC) from non-ROSC.
- Analysis used EtCO2 data from 1168 patients in the Pragmatic Airway Resuscitation Trial.
- Patients were stratified by witnessed status and initial EtCO2 levels: low (≤30 mmHg), moderate (31-49), and high (≥50).
- Group-based trajectory modeling identified upward or downward EtCO2 trajectory classes.
- In witnessed arrests, upward vs. downward trajectories showed non-overlapping confidence intervals after 8 minutes for low EtCO2, 12 for moderate, and 21 for high.
- For unwitnessed arrests, non-overlapping confidence intervals occurred at 7 minutes.
- EtCO2 trajectory monitoring (7-21 minutes depending on factors) can offer early prognostic guidance during OHCA resuscitation.