Assessing the trustworthiness of health guidelines recommendations: the Transparent, Rigorous, Usable, Standardised and Trustworthy Guide (TRUSTGUIDES) tools development - PubMed
2 hours ago
- #AI integration
- #trustworthiness assessment
- #health guidelines
- Development of TRUSTGUIDES tools aims to assess trustworthiness of health guideline recommendations, which includes transparency, rigor, usability, standardization, and trust.
- Existing tools for guideline appraisal lack comprehensive evaluation of individual recommendations and fail to incorporate recent methodological advances like living guidelines, GRADE, adaptation, and AI.
- TRUSTGUIDES defines trustworthiness as distinct from methodological quality, encompassing rigorous methods, transparency, independence, and applicability to determine user confidence in recommendations.
- The development process involves a multi-step mixed-methods approach, including scoping review, expert consultation, Delphi surveys, and validation of psychometric properties through factor analysis and item response theory.
- AI integration is considered both as a subject for assessment and as a methodological aid, with large language models compared against human reference standards to support tool application.
- Validation will compare TRUSTGUIDES with established instruments like GRADE, AGREE II, and PANELVIEW to ensure internal consistency, reliability, content validity, and construct validity.