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Axonopathy: mechanisms and potential therapeutic targets for neurodegenerative diseases - PubMed

5 hours ago
  • #neurodegenerative-diseases
  • #therapeutic-targets
  • #axonopathy
  • Axons are critical for neuronal homeostasis and their dysfunction (axonopathy) is an early mechanism in neurodegenerative diseases.
  • Axonopathy contributes to diseases like Alzheimer's, Parkinson's, Huntington's, and ALS.
  • Recent advances highlight axons as potential therapeutic targets for neurodegenerative diseases.
  • Key areas of focus include axonal transport, mitochondria, autophagy, and neurotrophic factors.