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Topical NAMPT activation restores mitophagic flux to rescue diabetic keratopathy via the NAD⁺/PINK1 pathway - PubMed

14 hours ago
  • #Mitophagy
  • #NAMPT
  • #Diabetic Keratopathy
  • Topical NAMPT activation helps restore mitophagic flux to treat diabetic keratopathy via the NAD+/PINK1 pathway.
  • The study was approved by ethics committees and conducted in compliance with the Declaration of Helsinki and ARVO guidelines.
  • Key keywords include Apoptosis, Diabetic keratopathy, Mitophagy, NAD, NAMPT, Neuroprotection, P7C3, and ROS.
  • The authors declare no competing interests.
  • References include studies on diabetes complications, tear production in diabetes, and new therapeutic approaches for diabetic keratopathy.