Spatial organization of tissue-resident memory T cells - PubMed
6 hours ago
- #T cells
- #Immunology
- #Tissue Memory
- TRM cells are long-lived in tissues, providing rapid local immunity.
- Defining TRM cells is challenging due to proving residency and antigen absence.
- Early priming and tissue imprinting shape TRM cell programming.
- TRM cells show intra-tissue heterogeneity, influenced by niche-level cues.
- They complement circulating memory T cells in immunological memory.