High dietary fiber is associated with improved outcomes in patients with melanoma and sarcoma treated with immunotherapy regardless of gut microbiome dysbiosis and social vulnerability - PubMed
6 hours ago
- #immunotherapy
- #melanoma
- #dietary-fiber
- High dietary fiber intake is linked to better outcomes in melanoma and sarcoma patients undergoing immunotherapy.
- Social vulnerability is inversely correlated with dietary fiber intake and negatively impacts gut microbiome composition.
- Patients with higher dietary fiber intake showed improved response to immune checkpoint blockade (ICB) therapy.
- No significant difference in overall survival (OS) was observed based on social vulnerability, but higher fiber intake was associated with better OS.
- The study suggests dietary fiber as a modifiable factor to enhance immunotherapy outcomes, especially in socially vulnerable patients.