SGLT2 inhibitors therapy in patients with acute Takotsubo syndrome - PubMed
4 days ago
- #Takotsubo syndrome
- #SGLT2 inhibitors
- #Myocardial edema
- SGLT2 inhibitors are evaluated for safety, tolerability, and effects on myocardial recovery and inflammation in acute Takotsubo syndrome (TTS).
- The study compared 22 SGLT2 inhibitors-treated TTS patients with 44 untreated patients using propensity-score matching.
- Treated patients showed significantly lower myocardial edema burden (septal and global T2 mapping values) and higher left ventricular ejection fraction (LVEF) compared to controls.
- No drug-related adverse effects were observed during hospitalization, and the discontinuation rate at follow-up was low (4.5%).
- The findings suggest that SGLT2 inhibitors may promote quicker recovery of myocardial function in acute TTS.