White matter micro- and macrostructure brain charts for the human lifespan - PubMed
3 hours ago
- #brain charts
- #lifespan
- #white matter
- White matter acts as the primary communication highway in the human brain, with disruptions linked to neurological, psychiatric, and developmental disorders.
- The study presents lifespan reference charts for white matter microstructure and macrostructure, mapping typical growth, maturation, and decline from birth to 100 years.
- Charts are based on processing and standardizing 35,120 brain scans from diverse global studies, establishing a normative benchmark for healthy brain development and aging.
- These open-access charts allow researchers and clinicians to quantify individual brain deviations from typical patterns and evaluate new data against normative baselines.
- The reference standard aims to facilitate future clinical and neuroscience studies by providing a tool to highlight disorder-related alterations in white matter pathways.