Integrating inflammation, insulin resistance, and visceral adiposity: the C-reactive protein-triglyceride-glucose-Chinese visceral adiposity (CTI-CVAI) index is associated with cardiovascular disease
3 hours ago
- #biomarkers
- #cohort study
- #cardiovascular disease
- The study developed a novel composite index, CTI-CVAI, integrating three key CVD pathways: inflammation, insulin resistance, and visceral adiposity.
- CTI-CVAI showed a strong, linear, dose-dependent association with increased cardiovascular disease (CVD) risk in Chinese adults with CKM stages 0-3.
- Using data from the CHARLS cohort (2011-2020), the highest quartile of CTI-CVAI was linked to a 2.07-fold higher CVD risk compared to the lowest quartile.
- The index improved risk reclassification over single biomarkers, offering a low-cost, accessible tool for early CVD prevention in high-risk populations.