Japan research uncovers how coffee constituent limit growth of colorectal cancer
6 hours ago
- #cancer research
- #coffee health benefits
- #molecular biology
- Japanese researchers discovered that caffeic acid in coffee suppresses colorectal cancer cell growth.
- Caffeic acid binds to the protein RPS5, linked to poor recovery in colorectal cancer patients.
- Suppressing RPS5 expression halts the cancer cell cycle at the DNA replication preparatory stage.
- Caffeic acid and RPS5 suppression reduce cyclin D1 levels, inhibiting cancer cell growth.
- The findings may lead to new cancer prevention and treatment strategies targeting RPS5.
- Researchers caution that the study is basic and does not directly link coffee intake to cancer prevention.