Amoxicillin-induced Erythema Scarlatiniforme Desquamativum Recidivans with cross-reactivity to cefadroxil in a child: A case report and review of literature - PubMed
7 days ago
- #paediatrics
- #drug-hypersensitivity
- #beta-lactams
- First documented pediatric case of generalized Erythema Scarlatiniforme Desquamativum Recidivans (ESDR) induced by amoxicillin.
- Cross-reactivity assessed with phenoxymethylpenicillin, oxacillin, and cefadroxil via oral provocation tests (OPTs).
- Positive reaction to cefadroxil indicates selective aminopenicillin-aminocephalosporin cross-reactivity.
- Naranjo score of 8 classifies the reaction as 'probable' triggered by amoxicillin.
- Emphasizes the importance of complete allergy work-up, including OPTs, for safe future therapeutic decisions.