Global Burden of Polycystic Ovary Syndrome: Socioeconomic Disparities, Reproductive Impacts, and Projections to 2050 - PubMed
4 days ago
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- #reproductive health
- Polycystic ovary syndrome (PCOS) affects 11%-13% of women globally, making it the most common endocrine disorder in reproductive-age women.
- From 1990 to 2021, global PCOS cases increased by 89.6%, from 36.65 million to 69.47 million, with an age-standardized prevalence rate of 1757.8 per 100,000 in 2021.
- High-middle SDI regions have the highest PCOS burden (ASPR: 5237.6 per 100,000), while low-SDI regions show the steepest rise (AAPC: 2.22).
- Infertility is the leading cause of years lived with disability (YLDs) due to PCOS, peaking at ages 25-29.
- Socioeconomic inequalities in PCOS burden decreased from 1990 to 2021 (Slope Index of Inequality from 28.55 to 22.28).
- Projections estimate 103.91 million PCOS cases by 2050, highlighting the need for improved screening, personalized treatments, and targeted interventions in low-SDI regions.