Introduction to Genomics for Engineers
4 days ago
- #DNA
- #genomics
- #cells
- This guide is written for computer scientists and engineers to introduce cancer genomics in a simplified, broad-strokes manner.
- Cells are the smallest units of life, containing genomes with DNA that encode genes and produce proteins.
- The bakery analogy compares the genome to a recipe book, genes to cake recipes, and proteins to physical cakes.
- DNA can be modeled as a ~3 billion character string of A, C, T, G, representing nucleotides in complementary strands.
- DNA is organized into chromosomes, with humans having 23 pairs, including autosomes and sex chromosomes.
- Genomes store hereditary information and when mutated can lead to diseases like cancer, enabling personalized medicine.