Non-invasive tests to guide hepatocellular carcinoma surveillance - PubMed

4 hours ago

Non-invasive tests like FIB-4 and liver stiffness measurement (LSM) are effective in predicting hepatocellular carcinoma (HCC) risk.
FIB-4 scores ≥1.75 and >2.67 align with LSM thresholds of ≥10 kPa and ≥15 kPa, respectively, in identifying patients at risk for HCC.
The study analyzed 6,143 patients and validated findings in the UK Biobank, showing FIB-4's comparable accuracy to LSM in predicting HCC.
FIB-4 can serve as a practical tool for HCC surveillance, especially where LSM is unavailable.
The findings support the use of FIB-4 in clinical practice to guide HCC surveillance strategies.

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