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Systemic Pharmacological Treatments for Chronic Plaque Psoriasis - PubMed

5 hours ago
  • #PASI 90
  • #systemic treatments
  • #psoriasis
  • Biologic therapies, especially IL-17 and IL-23 inhibitors, show the highest short-term efficacy in achieving PASI 90 for adults with moderate to severe plaque psoriasis.
  • Oral systemic treatments offer more moderate efficacy but are key alternatives for patients preferring non-injectable options.
  • Serious adverse events are uncommon across all systemic therapies and comparable to placebo in the short term.