Control of representation updating by higher-order thalamus enables history-based decision-making - PubMed
4 hours ago
- #sensory-history encoding
- #thalamocortical dynamics
- #neural basis of decision-making
- The study explores how the brain updates internal representations for decision-making when sensory information is ambiguous, focusing on interactions between the posterior parietal cortex (PPC) and the pulvinar (PUL) in mice.
- Findings show that PPC-PUL interactions are essential for maintaining stable sensory history representations, with the thalamic reticular nucleus (TRN) providing inhibitory control to facilitate updates based on recent sensory patterns.
- A mechanism involving TRN inhibition of PUL enables adaptive updating of encoded sensory history, highlighting a thalamocortical framework for tracking environmental changes.