Therapeutic Penetrating Keratoplasty for Aspergillus Fungal Keratitis: A Case Report - PubMed
7 hours ago
- #fungal keratitis
- #Aspergillus
- #therapeutic keratoplasty
- A 35-year-old farmer with fungal keratitis was successfully treated with therapeutic penetrating keratoplasty (TPK).
- The patient had a corneal ulcer following an ocular injury during farm work and did not improve with initial antifungal treatments.
- Diagnosis revealed Aspergillus lentulus, sensitive to voriconazole, but the condition worsened despite intensive therapy.
- Emergency TPK was performed, including removal of infected tissue and irrigation with voriconazole.
- Postoperative treatment included cyclosporine A instead of corticosteroids to preserve the graft.
- Four months post-surgery, the patient was infection-free with improving vision.
- TPK with anterior chamber lavage proved effective for fungal keratitis resistant to conventional treatments.