Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial - PubMed
5 hours ago
- #amino acids
- #sarcopenia
- #resistance exercise
- Combined resistance exercise (RE) and essential amino acid (EAA) intake enhances muscle fitness in older women.
- The study involved 96 healthy women aged ≥65, randomized into control, RE, EAA, or RE + EAA groups.
- RE + EAA group showed significant increases in muscle mass and improvements in senior fitness tests.
- Follistatin levels increased, and myostatin levels decreased in RE and RE + EAA groups.
- The follistatin/myostatin ratio increased most in the RE + EAA group.
- Inflammatory markers (IL-6, IL-1β, TNF-α) were reduced in RE and RE + EAA groups.
- The 12-week intervention was superior to RE or EAA alone in enhancing muscle health.