Tirzepatide on physical function in adults with overweight or obesity: A systematic review and meta-analysis - PubMed
3 days ago
- #Obesity
- #Tirzepatide
- #Physical Function
- Tirzepatide significantly improves physical function in adults with overweight or obesity.
- The study analyzed data from six RCTs involving 4531 participants, with 2802 receiving tirzepatide.
- Improvements were noted in both SF-36 physical function (MD 2.26 points) and IWQOL-Lite-CT physical function (MD 10.10 points).
- Subgroup analyses showed consistent benefits for both 10 mg and 15 mg doses of tirzepatide.
- The overall certainty of evidence was rated as moderate due to risk of bias and inconsistency across studies.
- High heterogeneity between studies suggests cautious interpretation of the pooled estimates.