Metformin-associated lactic acidosis in an elderly diabetic patient without classical risk factors: a case report - PubMed
14 hours ago
- #metformin
- #diabetes
- #lactic-acidosis
- Metformin is a first-line therapy for type 2 diabetes mellitus (T2DM) with a generally safe profile but carries a rare risk of lactic acidosis (MALA).
- Common risk factors for MALA include renal/hepatic impairment, excessive alcohol, poorly controlled diabetes, ketosis, prolonged fasting, and hypoxia-related conditions.
- This case report describes a 75-year-old T2DM patient with schizophrenia who developed MALA without any typical risk factors.
- The case highlights the need for high suspicion of MALA in all metformin users, regardless of apparent risk factors.
- Early recognition and prompt intervention are crucial for improving outcomes in MALA cases.