The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist - PubMed
4 hours ago
- #Interstitial Pneumonia
- #Pulmonary Fibrosis
- #Pathology Update
- The 2025 ATS/ERS classification expands beyond idiopathic interstitial pneumonias to include secondary causes, reflecting advances in understanding secondary versus idiopathic disease.
- It introduces a new subclassification system for interstitial disorders (fibrotic vs. non-fibrotic) and alveolar filling disorders, with additional patterns such as bronchiolocentric interstitial pneumonia.
- The update features improved terminology to better reflect histogenesis and emphasizes the importance of diagnostic confidence in biopsy evaluation, including the role of cryobiopsy.
- Pathologists are advised to report features indicating secondary causes over idiopathic disease and to apply this framework prospectively for diagnosis and research in interstitial pneumonia.